Case studies in modern drug discovery and development

상세정보

자료유형	단행본
서명/저자사항	Case studies in modern drug discovery and development/ edited by Xianhai Huang, Robert G. Aslanian.
개인저자	Huang, Xianhai.  Aslanian, Robert G.
발행사항	Hoboken, NJ: Wiley, c2012.
형태사항	xviii, 451 p.: ill; 27 cm.
ISBN	9780470601815 (cloth):
서지주기	Includes bibliographical references and index.
내용주기	Introduction: drug discovery in difficult times / Malcom MacCoss -- Discovery and development of the DPP-4 inhibitor JANUVIA? (Sitagliptin) / Emma R. Parmee ... [et al.] -- Olmesartan medoxiomil, an angiotensin II receptor blocker / Hiroaki Yanagisawa, Hiroyuki Koike, and Shinichiro Miura -- Discovery of heterocyclic phosphonic acids as novel AMP mimics that are potent and selective fructose-1,6-bisphosphatase inhibitors and elicit potent glucose-lowering effects in diabetic animals and human / Qun Dang, and Mark D. Erion -- Setting the paradigm of targeted drugs for the treatment of cancer : Imatinib and Nilotinib therapies for chronic myelogenous leukaemia / Paul W. Manley and Jurg Zimmermann -- Amrubicin, a completely synthetic 9-aminoanthracycline, for extensive-disease small-cell lung cancer / Mitsuharu Hanada -- The discovery of dual IGF-1R and IR inhibitor FQIT for the treatment of cancer / Meizhong Jin, Elizabeth Buck, and Mark J. Mulvihill -- Discovery and development of Montelukast (Singulair?) / Robert N. Young -- Discovery and development of Maraviroc, a CCR5 antagonist for the treatment of HIV Infection / Patrick Dorr, Blanda Stammen, Elna van der Ryst -- Discovery of antimalarial drug Artemisinin and beyond / Ao Zhang, Weiwei Mao, Yu Zhang -- Discovery and process development of MK-4965, a potent non-nucleoside reverse transcriptase inhibitor / Yong-Li Zhong, Thomas J. Tucker, and Jingjun Yin -- Discovery of Boceprevir and Narlaprevir : the first and second generation of HCV NS3 protease inhibitors / Kevin X. Chen, F. George Njoroge -- The discovery of Samsca (Tolvaptan) : the first oral nonpeptide vasopressin receptor antagonist / Kazumi Kondo, Yoshitaka Yamamura -- SILODOSIN (Urief?, Rapaflo?, Thrupas?, Urorec?, SilodixTM) : a selective a1A adrenoceptor antagonist for the treatment of benign prostatic hyperplasia / Masaki Yoshida ... [et al.] -- Raloxifene : a selective estrogen receptor modulator (SERM) / Jeffrey A. Dodge and Henry U. Bryant.
일반주제명	Drug Discovery. Drug Evaluation.
분류기호(NLMC)	QV 744
분류기호(DDC)	615.19
언어	영어