Advancing disease modeling in animal-based research in support of precision medicine [electronic resource] : proceedings of a workshop

상세정보

자료유형	단행본
서명/저자사항	Advancing disease modeling in animal-based research in support of precision medicine [electronic resource]: proceedings of a workshop / Erin Hammers Forstag and Lida Anestidou, rapporteurs ; Roundtable on Science and Welfare in Laboratory Animal Use, Institute for Laboratory Animal Research, Division of Earth and Life Studies, the National Academies of Sciences, Engineering, Medicine.
개인저자	Forstag, Erin Hammers, rapporteur. Anestidou, Lida, 1965- rapporteur.
단체저자명	National Academies of Sciences, Engineering, and Medicine (U.S.). Roundtable on Science and Welfare in Laboratory Animal Use,issuing body.
발행사항	Washington, DC: the Nationeal Academies Press, [2018].
형태사항	1 online resource (xiii, 122 pages) : ill.
기타형태 저록	Print version: Forstag, Erin Hammers. Advancing disease modeling in animal-based research in support of precision medicine : proceedings of a Workshop Washington, D.C. : National Academies Press,c2018 9780309471169
ISBN	9780309471190 0309471192
서지주기	Includes bibliographical references (pages 90-94).
내용주기	Introduction to precision medicine and animal models -- Existing precision medicine initiatives -- The promise and perils of animal models -- Reproducibility and predictivity -- In vitro alternatives to animal models -- Assessing safety and toxicology -- Patient perspectives -- Reflections on the workshop -- References.
요약	"Precision medicine is focused on the individual and will require the rapid and accurate identification and prioritization of causative factors of disease. To move forward and accelerate the delivery of the anticipated benefits of precision medicine, developing predictable, reproducible, and reliable animal models will be essential. In order to explore the topic of animal-based research and its relevance to precision medicine, the National Academies of Sciences, Engineering, and Medicine convened a 2-day workshop on October 5 and 6, 2017. The workshop was designed to focus on the development, implementation, and interpretation of model organisms to advance and accelerate the field of precision medicine. Participants examined the extent to which next-generation animal models, designed using patient data and phenotyping platforms targeted to reveal and inform disease mechanisms, will be essential to the successful implementation of precision medicine. This publication summarizes the presentations and discussions from the workshop"--Publisher's description.
회의명	Advancing Disease Modeling in Animal-Based Research in Support of Precision Medicine (Workshop) (2017 : Washington, D.C.).
일반주제명	Animal models in research --Congresses. Personalized medicine --Congresses. HEALTH & FITNESS / Diseases / General. MEDICAL / Clinical Medicine. MEDICAL / Diseases. MEDICAL / Evidence-Based Medicine. MEDICAL / Internal Medicine.
분류기호(DDC)	616.027
언어	영어
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