Contemporary issues for protecting patients in cancer research [electronic resource] : workshop summary

상세정보

자료유형	단행본
서명/저자사항	Contemporary issues for protecting patients in cancer research [electronic resource]: workshop summary / Sharyl J. Nass and Margie Patlak, rapporteurs; National Cancer Policy Forum, Board on Health Care Services, Institute of Medicine of the National Academies.
개인저자	Nass, Sharyl J., rapporteur. Patlak, Margie, rapporteur.
단체저자명	National Cancer Policy Forum (U.S.),issuing body.
발행사항	Washington, D.C.: National Academies Press, [2014].
형태사항	1 online resource (xvii, 74 pages) : illustrations.
ISBN	9780309306676 0309306671
서지주기	Includes bibliographical references.
내용주기	Introduction -- Current regulatory arena -- Common rule and HIPAA -- Shortcomings of current regulations and guidances -- Context -- Data deindentification -- Impediment to quality improvement and learning -- Varied interpretation -- Misaligned incentives -- Lack of harmonization with international standards -- Informed consent forms -- Informed consent process -- Consent tools -- Beyond consent -- HITECH -- Advanced notice of proposed rulemaking -- Patient perspectives on research protections -- Ethical challenges of genetic advances -- Patient consent for use of archived biospecimens -- Return of research results -- Clinically actionable findings -- Context matters -- Who pays -- Biospecimens from deceased participants -- The changing context of research and care -- Oversight in a learning health care system -- Oversight of pragmatic trials -- Multisite studies and IRB review -- Central IRBs -- New England Reliance Agreement -- Value of local IRBs -- Educational needs -- Research needs -- Wrap-up.
요약	"In the nearly 40 years since implementation of federal regulations governing the protection of human participants in research, the number of clinical studies has grown exponentially. These studies have become more complex, with multisite trials now common, and there is increasing use of archived biospecimens and related data, including genomics data. In addition, growing emphasis on targeted cancer therapies requires greater collaboration and sharing of research data to ensure that rare patient subsets are adequately represented. Electronic records enable more extensive data collection and mining, but also raise concerns about the potential for inappropriate or unauthorized use of data, bringing patient protections into a new landscape. There are also long-standing concerns about the processes and forms used to obtain informed consent from patients participating in clinical studies. These changes and challenges raise new ethical and practical questions for the oversight of clinical studies, and for protecting patients and their health information in an efficient manner that does not compromise the progress of biomedical research. Contemporary Issues for Protecting Patients in Cancer Research is the summary of a workshop convened by the National Cancer Policy Forum of the Institute of Medicine in February 2014 to explore contemporary issues in human subjects protections as they pertain to cancer research, with the goal of identifying potential relevant policy actions. Clinical researchers, government officials, members of Institutional Review Boards, and patient advocates met to discuss clinical cancer research and oversight. This report examines current regulatory provisions that may not adequately protect patients or may be hindering research, and discusses potential strategies and actions to address those challenges"--Publisher's description.
회의명	Contemporary Issues in Human Subjects Protections (Workshop) (2014 : Washington, D.C.),
일반주제명	Human experimentation in medicine --United States --Congresses. Human experimentation in medicine --Moral and ethical aspects --United States --Congresses. Patients --Civil rights --United States --Congresses. Clinical trials --United States --Congresses. Cancer --Research --United States --Congresses. Medical ethics --United States --Congresses. Human Experimentation --standards --United States --Congresses. Clinical Trials as Topic --standards --United States --Congresses. Patient Rights --United States --Congresses. Neoplasms --United States --Congresses. Ethics, Research --United States --Congresses. Ethics Committees, Research --United States --Congresses. Informed Consent --United States --Congresses. Research Subjects --United States --Congresses. Confidentiality --standards --United States --Congresses. Electronic Health Records --standards --United States --Congresses. Privacy --United States --Congresses. Researcher-Subject Relations --United States --Congresses.
분류기호(DDC)	174.28
언어	영어
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