The heat transfer characteristics of R134a flow boiling in a horizontal tube of an evaporator section for a refrigeration system of 310-W capacity are investigated experimentally and numerically. The experimental work was conducted using an evaporator tube test section of inner diameter 5.8mm and length 600mm. The ranges of investigated experimental data for heat flux, mass flux, saturation temperature and vapor quality were 13.8–36.6 kW/m2, 52–105kg/m2 s, −15 −–−3.7∘ C and 0.2–1, respectively. Numerical analysis was based on two-phase flow turbulent model and this model was solved using the Ansys-18 code. The results showed that the effects of heat flux, mass velocity and saturation temperature on local heat transfer coefficient and pressure drop were greater compared to that of the refrigerant vapor quality. The enhancements in local heat transfer coefficient due to the increase in heat flux, mass and saturation temperature were 38%, 57% and 64%, respectively, within the prescribed test conditions. The influence of mass flux variation on pressure drop along the evaporator channel was higher in the range of 27% compared to the heat flux effect. The average deviations between experimental and numerical results of heat transfer coefficient and pressure gradient were 14% and 17%, respectively, while the same between the experimental and predicted results were 16% and 33%, respectively.